ChloroquineV1, Main, Exploration, bibRecord, 001510

Serum levels of soluble CD26 and CD30 and their clinical significance in patients with rheumatoid arthritis

Identifieur interne : 001510 ( Main/Exploration ); précédent : 001509; suivant : 001511

Serum levels of soluble CD26 and CD30 and their clinical significance in patients with rheumatoid arthritis

Auteurs : Hasan Ulusoy [Turquie] ; Ayhan Kamanli [Turquie] ; Necip Ilhan [Turquie] ; Omer Kuru [Turquie] ; Sule Arslan [Turquie] ; Gokhan Alkan [Turquie] ; Salih Ozgocmen [Turquie]

Source :

Rheumatology International [ 0172-8172 ] ; 2012-12-01.

RBID : ISTEX:38BC2B5441A26827FE895F3C71088AA5C9235E20

English descriptors

KwdEn :
- CD26, CD30, Disease activity, Rheumatoid arthritis.

Abstract

Abstract: The aim of this study was to assess serum levels and clinical significance of soluble CD26 (sCD26) and soluble CD30 (sCD30) in patients with rheumatoid arthritis (RA). Forty-eight patients with RA and 30 healthy controls were enrolled. Serum sCD26 and sCD30 levels were measured using ELISA. Serum sCD26 levels were significantly lower (P = 0.011), whereas sCD30 levels were higher (P = 0.008) in patients with RA than controls. Serum levels of sCD30 correlated significantly with clinical and laboratory parameters of disease activity like erythrocyte sedimentation rate, C-reactive protein, disease activity scores-28 and health assessment questionnaire score; however, sCD26 levels did not correlate any of these activity parameters. These results suggest that serum sCD30 levels increased and correlated significantly with disease activity, indicating a novel follow-up parameter in RA. Serum levels of sCD26 may be lessen but not related to disease activity in RA.

Url:

https://api.istex.fr/ark:/67375/VQC-PH37VWL8-B/fulltext.pdf

DOI: 10.1007/s00296-011-2302-3

Affiliations:

Turquie

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Le document en format XML

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<front><div type="abstract" xml:lang="en">Abstract: The aim of this study was to assess serum levels and clinical significance of soluble CD26 (sCD26) and soluble CD30 (sCD30) in patients with rheumatoid arthritis (RA). Forty-eight patients with RA and 30 healthy controls were enrolled. Serum sCD26 and sCD30 levels were measured using ELISA. Serum sCD26 levels were significantly lower (P = 0.011), whereas sCD30 levels were higher (P = 0.008) in patients with RA than controls. Serum levels of sCD30 correlated significantly with clinical and laboratory parameters of disease activity like erythrocyte sedimentation rate, C-reactive protein, disease activity scores-28 and health assessment questionnaire score; however, sCD26 levels did not correlate any of these activity parameters. These results suggest that serum sCD30 levels increased and correlated significantly with disease activity, indicating a novel follow-up parameter in RA. Serum levels of sCD26 may be lessen but not related to disease activity in RA.</div>
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Serum levels of soluble CD26 and CD30 and their clinical significance in patients with rheumatoid arthritis

Serum levels of soluble CD26 and CD30 and their clinical significance in patients with rheumatoid arthritis

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri